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Hydroxyl Methylbutyrate (HMB) for strength and getting lean

HMB has been widely publicized and has been one of the more popular supplements for over a decade. HMB is a metabolite of the branch chained amino acid leucine. With claims like increased strength, muscle size, recovery and fat oxidation, it sounds too good to be true. In fact, a publisher of a very successful magazine referred to using HMB akin to using the anabolic steroid deca durabolin. Unfortunately, the claims made about HMB don’t seem to hold up in the research.

A study published in the Journal of Strength and Conditioning, performed a met-analysis of 9 studies. The analysis was comprised of 394 subjects between the ages of 21 and 25. Some of the subjects had training experience and some didn’t.

The major findings of this meta-analysis are that HMB supplementation results in a small, beneficial increase to overall strength in untrained lifters but has a negligible effect on trained lifters. Furthermore, in untrained lifters, HMB results in a small to possibly moderate increase in lower-body strength, but it has only a negligible effect on upper-body strength. In contrast, all strength outcomes are insignificant in trained lifters. In both trained and untrained lifters, the effect of HMB supplementation on body composition is negligible.

In my view HMB is a waste of money. The only gains made were small strength gains in untrained individuals? Why would any researchers analyzing a supplement, looking for strength or lean body mass gains, use untrained individuals? They are going to make gains, especially in the first few months, just by working out. I’m amazed at how so many studies are poorly performed and yet, are still published.

Testosterone’s time sensitive side effects

Low testosterone (T) symptoms may include low sex drive, erectile dysfunction, fewer sexual thoughts, mood problems, fatigue, loss of muscle, poor concentration, sleep disturbances, and fewer morning erections. Low T is also associated with several chronic medical conditions, including obesity, diabetes, osteoporosis, depression, and cardiovascular disease.

Men who get treated for low T have a very positive experience. The changes in appearance and mental state can be very profound. Interestingly, these positive changes associated with T therapy, have been found to occur at different times. A study from the University of Koln in Germany analyzed the relationship of time following administration vs. the effects on sexual functioning and mood on forty subjects. Researchers found sexual thoughts and fantasies occurred within weeks of initiating T therapy. Total number of erections rose steadily and peaked at 9 weeks. Ejaculations per week steadily rose and plateaued over 12 weeks. Depression decreased gradually and leveled off at 6 weeks. Mental concentration improved within the first 3 weeks, but overall mood did not improve until weeks 6 – 9.
The Aging Male 2009, 12: 113-118

Food additive makes you fat

Monosodium Glutamate (MSG) is a widely used food additive that may lead to obesity. It is often present in processed foods although it is frequently not clearly labeled. MSG is frequently seen hiding behind such innocent-sounding names as hydrolyzed protein, vegetable protein, soy protein isolate, soy protein concentrate, whey protein, and natural flavoring, spices, enzymes, autolyzed yeast extract, stock, broth and carrageenan. If MSG was as benign as the food industry says it is, why do they have to disguise the name?

In a study published in the American Journal of Clinical Nutrition, researchers followed more than 10,000 adults in China for about 5.5 years on average. The researchers measured MSG intake directly by before-and-after weighing of products, such as bottles of soy sauce, to see how much people ate. They also asked people to estimate their intake over three 24-hour periods. Men and women who ate the most MSG (a median of 5 grams a day) were about 30 percent more likely to become overweight by the end of the study than those who ate the least amount of the flavoring (less than a half-gram a day), the researchers found. After excluding people who were overweight at the start of the study, the risk rose to 33 percent.”

Is keeping your hair worth it?

Pharmaceuticals used to treat male pattern baldness (MPB) like Proscar (finasteride), work by decreasing serum levels dihydrotestosterone (DHT). DHT has been called the most potent of all androgens (male sex hormones), and is the major factor in MPB.

The current theory is that DHT binds to the hair follicle and prevents ribonucleic acid (RNA) from functioning. RNA is responsible for protein synthesis. In a nut shell, if the RNA doesn’t function, the follicle cannot create protein and stunts hair growth. Decreasing DHT levels will prevent baldness, but is it worth the side effects?

A Study reported in The Journal of Sexual Medicine, conducted standardized interviews with 71 healthy men taking finasteride to prevent baldness. 94% of the participants developed low libido, 92% developed erectile dysfunction, 92% developed decreased arousal, and 69% developed problems with orgasm. So, if you’re willing to give up your sex life to have a full head of hair, go ahead and take Proscar.

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