Whoever thought that spider venom could could be the answer for erectile dysfunction, however, emergency room visits in Brazil with victims of spider bites displaying priapism, or unrelenting and painful erections, got doctors thinking.
Some research has led to the isolation of an alternative way to help men attain and sustain an erection.
Viagra, Levitra and other ED drugs on the market work by inhibiting an enzyme called PDE5. To get an erection, a man’s body must release nitric oxide, which relaxes the smooth muscle around the arteries of the penis, allowing for his blood vessels to dilate.
The nitric oxide is a first step in a series of chemical reactions that allow this muscle relaxation to take place. One step in the series is cGMP, a signaling molecule that acts to keep the muscles relaxed. PDE5 degrades cGMP. That’s a good thing for ensuring that erections don’t last forever, but too much PDE5 can mean an erection doesn’t happen at all. By blocking the enzyme, PDE5 inhibitors solve the problem.
The spider toxin works differently. Instead of affecting PDE5, the compound seems to trigger nitric oxide release, acting directly to relax the smooth muscles. Because about 30 percent of patients don’t respond to PDE5 inhibitors, the toxin could provide an alternative to ED treatments currently on the market, Nunes said.
Be careful when you fool around you might just fall in love.
Scientists have found that the same part of the brain which is stimulated by lust is also the part of the brain responsible for bonding and love.
In order to map out the location of sexual desire and love, researchers reviewed 20 studies that used fMRI technology. First, they looked at the regions of the brain that lit up when sparked by love. They then compared the findings of all the papers to see what regions were activated when someone felt aroused or amorous.
What they discovered was a bit surprising — love and sexual desire both activate the striatum, showing a continuum from sexual desire to love. Each feeling impacts a different area of the striatum.
Sexual desire activates the ventral striatum, the brain’s reward system. When someone enjoys a great dessert or an orgasm, it’s the ventral striatum that flickers with life. Love sparks activity in the dorsal striatum, which is associated with drug addiction.
Pharmaceuticals used to treat male pattern baldness (MPB) like Proscar (finasteride), work by decreasing serum levels dihydrotestosterone (DHT). DHT has been called the most potent of all androgens (male sex hormones), and is the major factor in MPB.
The current theory is that DHT binds to the hair follicle and prevents ribonucleic acid (RNA) from functioning. RNA is responsible for protein synthesis. In a nut shell, if the RNA doesn’t function, the follicle cannot create protein and stunts hair growth. Decreasing DHT levels will prevent baldness, but is it worth the side effects?
A Study reported in The Journal of Sexual Medicine, conducted standardized interviews with 71 healthy men taking finasteride to prevent baldness. 94% of the participants developed low libido, 92% developed erectile dysfunction, 92% developed decreased arousal, and 69% developed problems with orgasm. So, if you’re willing to give up your sex life to have a full head of hair, go ahead and take Proscar.