Low testosterone and depression

Low testosterone levels in older men are associated with an increased risk of depression, according to an Australian study.

Between 2001 and 2004, researchers at the University of Western Australia in Perth studied 3,987 males aged 71 to 89. The men provided demographic and health information and were tested for depression and cognitive difficulties. The researchers also checked the men’s testosterone levels.

The 203 men who met the criteria for depression had significantly lower total and free (not bound to proteins) testosterone levels than those who weren’t depressed. After controlling for other factors, such as cognitive scores, education level and body-mass index, the researchers concluded that men in the lowest quintile (20 percent) of free testosterone were three times more likely to have depression compared to those in the highest quintile.

The findings were published in the March issue of the Archives of General Psychiatry.

There is more and more evidence mounting for medically supervised hormone replacement therapy. 
 

Testosterone protects against heart disease

Low testosterone levels are associated with a greater risk of heart attacks, diabetes, abdominal fat deposition and abnormal blood lipid levels. Cytokins, which cause inflammation in the arteries, are the latest suspected cause of heart disease. British researchers suggest testosterone suppresses cytokins and also boosts the immune system, thereby preventing heart disease. (J Endocrinol, 178: 373-380, 2003)

Diet and Tesosterone Levels

A recent study performed in Finland included men ages 49 to 73 who underwent 21 weeks of supervised training and dieting. Half the subjects ate a high-fiber, low-fat diet including grains, fruits, vegetables, lean meat, fish and dairy. This diet led to a decline in men’s testosterone. The study also found that subjects who ate more protein and had a fat intake of at least 30 percent had higher levels of testosterone and improved muscular gains. Eating less than 30 percent fat seemed to adversely affect hormone levels. The amount of fiber did not have an adverse effect on building muscle or hormone levels. (Intl J Sports Med. 28(12):1070-1076)
(Did you know… 10-30-08)

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