Testosterone’s time sensitive side effects

Low testosterone (T) symptoms may include low sex drive, erectile dysfunction, fewer sexual thoughts, mood problems, fatigue, loss of muscle, poor concentration, sleep disturbances, and fewer morning erections. Low T is also associated with several chronic medical conditions, including obesity, diabetes, osteoporosis, depression, and cardiovascular disease.

Men who get treated for low T have a very positive experience. The changes in appearance and mental state can be very profound. Interestingly, these positive changes associated with T therapy, have been found to occur at different times. A study from the University of Koln in Germany analyzed the relationship of time following administration vs. the effects on sexual functioning and mood on forty subjects. Researchers found sexual thoughts and fantasies occurred within weeks of initiating T therapy. Total number of erections rose steadily and peaked at 9 weeks. Ejaculations per week steadily rose and plateaued over 12 weeks. Depression decreased gradually and leveled off at 6 weeks. Mental concentration improved within the first 3 weeks, but overall mood did not improve until weeks 6 – 9.
The Aging Male 2009, 12: 113-118

Exercise induced hormone changes do not promote muscular gains

Exercise induced endogenous hormone levels have been studied extensively. Researchers have examined how the different components of training including sets, repetitions, load and rest intervals affect serum levels of hormones such as testosterone, growth hormone and cortisol. Many studies have demonstrated there is an acute increase in serum levels of anabolic hormones after intense resistance exercise.

To be more specific, high intensity exercise coupled with short rest intervals that is performed with large muscle groups are associated with large rises in these hormones when compared to other training methods. Conversely, training small muscle groups like the biceps has been shown to have no effect on serum hormone levels. Because of the findings in many studies, training programs have been constructed to maximize the post-exercise rise in these hormones based on the assertion that exercise-induced increases in hormones like testosterone and GH will enhance muscle size and strength. But, considering the fact that these increases in hormone levels are very small and of short duration, will they produce muscular gains.

A study from the Kinesiology Dept. of McMaster University in Canada found that exercise induced hormone levels had no effect on muscle size or strength after 15 weeks of resistance training.

There is evidence that a minimal basal level of testosterone is required to support strength and hypertrophy gains, which are otherwise attenuated. Therefore, the hormone-sensitive processes that underpin muscle anabolism at hypo- and supra-physiological hormone levels are not being activated appreciably by exercise-induced increases in hormone availability or at least do not result in any measurable enhancement of strength or hypertrophy.

(J Appl Physiol 108(1); 2010)

A true fat burner, GABA.

There’s a very effective fat burner that’s available over the counter, and it’s been around since 1883? Gamma-Aminobutyric Acid, more commonly known as GABA, is a powerful amino acid that is classified as a neurotransmitter in the brain. It acts as a balancer of excitation and relaxation. Its ability to burn fat is actually secondary. GABA stimulates the anterior pituitary gland, leading to an increased output of Human Growth Hormone. HGH is known to have anti-aging effects and lowers body-fat levels. One study conducted by the First Medical Clinic at the University of Milan found a five-fold increase in HGH levels of 19 subjects after 90 minutes of consuming 5gms of GABA. The 18 placebo subjects in the same study showed no increase in HGH output. This is an excellent product for those who can’t afford to go to an anti-aging clinic but want the benefits of HGH.

I’ve used this product on and of since the early eighties and have had good success. I always notice that I get a little leaner, sleep better and have a better overall wellbeing.

Soy lecithin, hormone replacement, high fat diets and HFCS

Mike weighs in on the pros and cons of hormone replacement therapy, soy lecithin, creatine and HFCS. He also reminds us that while there is a lot of good information on the internet, it’s important to research and consult with experts before using a product. Just because a product is legal doesn’t mean it’s safe or that it works.

Here’s a sample from the article:

Q: Hi Mike,

I was doing some research on HGH in my downtime, and the use of it to treat chronic conditions and developmental issues. Now, I came across this website http://www.rajeun.net/ as a result of my surfing. I had a look at the eight-point anti-aging program this guy has sorted out for himself and thought to myself, ?Gee Justin, be pretty cool if that worked, right??

Now some of it sounds like the usual bunkum; EDTA chelation seems to fit into that category for example.

But — and it’s a big but — in your opinion, if this guy keeps at what he’s been doing, does he have a routine that might give him an advantage over the rest of us when it comes to staying healthier for that bit longer? And following up, if you yourself wanted to go about living for a very long time, would you go down the same path this dude is going down?

In closing, respect for all for your time and encouragement Mike, a whole heap of people appreciate your attitude and your efforts in keeping guys fitter, healthier and happier.

Best regards.

A: Justin,

When it comes to living longer, does it give him an advantage over us? I don’t think there is enough evidence to answer that question. One thing is for sure, your quality of life definitely improves. Men who properly use hormone replacement therapy show an elevated sense of well-being and mood. If it didn’t work, it wouldn?t be such a huge business. There are anti-aging clinics popping up all over the world.

There are parts of his program however, that are a little suspect. Two that jump out at me are EDTA chelation for getting rid of metals in the body, and taking Vermoc to get rid of parasites. My advice to Ellis is to get the hell out of that God-forsaken toilet of a country.

Another part of his program that I take exception to is his endorsement of using Erythropoietin or EPO. EPO is a drug used in the clinical setting to increase hematocrit (red blood cell) levels. EPO is a natural substance produced by the kidneys that stimulates bone marrow to manufacture red blood cells. This drug, if used improperly, can result in death — as seen with Olympic athletes trying to gain an edge in endurance events.

Low hematocrit levels can be caused by many different conditions including blood loss, chemotherapy, HIV or nutritional deficiencies. Obviously, if the cause is nutritional, you’d want to use supplements, not a drug. Just because your hematocrit is low normal, it is no reason to jump on EPO. What Mr. Mexico doesn’t understand is that the drugs he is on, especially testosterone, increases your hematocrit levels. I believe Ellis’ site is a little on the irresponsible side.

Mike

Did you know?

Bullz-Eye.com Fitness Editor Mike Furci answers readers questions about water, U.S. hospitals and myths about salt.

…it?s not necessary to drink eight 8-ounce glasses of water a day to maintain optimum health? We?ve been told this arbitrary recommendation for years. There is little evidence for or against any of the supposed benefits of extra water, such as increased toxin excretion, improved skin tone, lessened hunger, and reduced headache frequency. A review of the available research concludes that for average healthy people, more water doesn?t mean better health. (Mercola.com newsletter)

To read the rest of the Q&A, click here.

Did You Know?

In his latest edition of ?Did You Know??, Mike Furci tackles such topics as anabolic steroids and their link (or lack of a link) to dangerous side effects, muscle contracting while working out and low testosterone levels and whether or not they can be associated with heart disease, diabetes and decreased libido.

BLF?all the actual data and medical studies on healthy individuals (adults) show no conclusions that physiological replacement doses of testosterone or other anabolic steroids are dangerous or cause side effects that do not reverse with cessation?

Moreover, in males who maintain physiological high normal levels, there appears to be health-promoting benefits associated with steroids. All the evidence contradicts the anti-steroid media blitz that started in the 80?s and continues today.

Approximately 25 years ago, Dr. Bob Goldman took a ride on the media feeding frenzy train and wrote a book, ?Death in the Locker Room.? This book puts steroids in the same class with alcohol and other recreational drugs as far as the dangers of usage. Since its release and despite the enormous increase in their use and dosage, there has not been one death attributable to steroids. (Planet Muscle Aug/Sept 2008: 72)

(Read the entire article here.)

Diet and Tesosterone Levels

A recent study performed in Finland included men ages 49 to 73 who underwent 21 weeks of supervised training and dieting. Half the subjects ate a high-fiber, low-fat diet including grains, fruits, vegetables, lean meat, fish and dairy. This diet led to a decline in men?s testosterone. The study also found that subjects who ate more protein and had a fat intake of at least 30 percent had higher levels of testosterone and improved muscular gains. Eating less than 30 percent fat seemed to adversely affect hormone levels. The amount of fiber did not have an adverse effect on building muscle or hormone levels. (Intl J Sports Med. 28(12):1070-1076)
(Did you know… 10-30-08)

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