Glutathione, the antiaging secret

Have you ever heard of glutathione (pronounced; gloota-thigh-own)? Neither has almost anyone else. Many researchers say it’s probably the most important substance we require to stay healthy. Many go as far to say it’s the secret to prevent aging. So where’s Oprah, and the rest of the media? A quick search of the term “glutathione” on PubMed.gov reveals 94,117 scholarly articles, reviews and abstracts.

Present in every cell of our body, glutathione levels just might be one of the best biochemical markers there is; the higher your glutathione levels are the healthier you will be. Glutathione deficiency is found in almost all patients with extreme illnesses, e.g., cancer, heart disease, Parkinson’s disease, Alzheimer’s, arthritis, liver disease, diabetes and more. In fact, researchers are concluding glutathione deficiency may play a role in patients with schizophrenia. In cerebrospinal fluid of drug-free schizophrenic patients, a significant decrease in the level of total glutathione was observed as compared to controls. EJN

Glutathione’s importance to a properly functioning immune system has been shown in many studies. According to Dr. Gustavo Bounous, “The limiting factor for the proper activity and multiplication of our lymphocytes (white blood cells) is the availability of glutathione”.

Every day our bodies are exposed to stress, pollution, infection, drugs (illicit or licit) and alcohol, poor diet, infections and injury, which drain our bodies of glutathione; this depletion leaves our bodies susceptible to high levels of oxidative stress, which leads to aging, disease and eventual death. I predict that concern about glutathione levels will eventually be on par with other preventative health issues.

Coffee cuts agressive cancer risk

A study that involved 5929 Swedish women, found a 33 percent to 57 percent lower risk for ER-negative cancer (the most aggressive type of breast cancer) than did those who drank less than one cup a day.

“Now, we don’t have all the details,” he cautioned. “We don’t know, for example, what specific type of coffee we’re talking about here. But what we do know is that the protective effect is quite striking and remains even after adjusting for a lot of other factors that have the potential to play a protective role. And we know that we’re talking about what we could call a relatively normal amount of coffee drinking. Certainly we’re not talking about consuming gigantic amounts of coffee. So, this is a very intriguing finding.”

HealthDay

Now the challenge is finding what it is in coffee that produces this protective effect, and if it will work with other types of cancer.

Hot dogs better than chicken?

Many people when shopping for a convenient ready to eat meat at the grocery store would choose rotisserie chicken over hot dogs or pepperoni, but as it turns out in a new study, they’d be wrong. Surprisingly, according to a new study, hot dogs and similar meats like pepperoni and deli meats are relatively free from carcinogenic compounds, and rotisserie chicken would be the riskier option.

The carcinogens in question are heterocyclic amines (HCAs), which are compounds found in meat that has been fried, grilled or cooked at high temperatures. Diets high in HCAs from meat increase people’s risk of stomach, breast and colon cancers, according to the National Cancer Institute.

Researchers from Kansas State University tested the HCA levels of eight popular ready-to-eat meat products: beef hot dogs, beef-pork-turkey hot dogs, deli roast beef, deli ham, deli turkey, fully cooked bacon, pepperoni and rotisserie chicken.

Pepperoni had the lowest levels of HCAs; hot dogs and deli meat came in second. Overall, these products were low in HCAs, researchers said, while cooked bacon and rotisserie chicken meat had the highest levels. However, rotisserie chicken skin had the highest levels of HCAs overall.

But, before you go purchase pepperoni, consider that its low HCA levels may have to do with processing, which is in itself a health hazard. According to a KSU statement.

Remember, You cannot judge the danger of a food by its HCA content alone, which is based on the manner in which its been cooked. You also have to evaluate all those added ingredients, such as preservatives, flavoring, and food colors. Hot dogs, deli meats and bacon are notorious for their nitrite content, so even though they might be low in HCA’s, they are far from healthful.

Vitamin D anticancer research project

Vitamin D3, which is technically a prehormone, has a whole host of benefits. This invaluable substance has a role in preventing or treating many diseases including cancer. Below you’ll find a letter I received as being a participant in a Vitamin D study, the results of which were published in the International Journal of Cancer Research and Treatment

GrassrootsHealth New Research Publication in the Anticancer Research Journal, 2/21/2011
Dear Michael,

Congratulations and thanks to absolutely everyone who has participated in and supported this project! According to one of our panel members, Dr. Anthony Norman:

“This paper provides a long awaited insight into a dose-response relationship between orally administered vitamin D3 and the resulting levels of serum 25(OH)D in over 3600 citizens. The results will allow a new definition of high vitamin D dose safety and reduce concerns about toxicity. This is a landmark contribution in the vitamin D nutrition field!”
Anthony Norman
Distinguished Professor of Biochemistry & Biomedical Sciences, Emeritus
University of California Riverside

Key findings:

There were 3667 people’s first test data reported on

No suggestions of toxicity were reported even up to intakes as high as 40,000 IU/day (not a recommended amount, however)

It’s going to take about 9600 IU/day to get 97.5% (almost everyone) to the 40 ng/ml level. Individual variations however range from 0 to over 50,000 IU/day!

Testing is necessary to determine what the starting serum level is and how to adjust intake

It took 3 tests (1 year) to determine the optimal dose for each individual

The NEW rule of thumb for dosing will be changed. We’ll publish a chart for all very shortly. Currently, it is stated that you can increase the serum level by 10 ng/ml with 1000 IU/day. Per our research, this is true only when starting at about 10 ng/ml. If you want to go from 50 to 60 ng/ml, it will take an additional 2000 IU/day (i.e., the rise is only 5 ng/ml for each 1000 IU/day).

Please visit our website, GrassrootsHealth and listen to the interviews with the study’s authors, Dr. Cedric Garland and Dr. Robert Heaney. They both speak to the significance to public health of this study.

Another key item that I am very aware of is the public’s readiness to ‘take charge’ of their own health. With this view and the information to make it happen, we are bound to see some very exciting things with own health!

The research article is ‘open access’ so that everyone can download and read it! Please do so here: GrassrootsHealth Research Article

Again, very, very many thanks to all of you for your participation and support. You are helping change the face of public health! We CAN move to a much more ‘preventive’ model of healthcare. Please let me know at any time how we can best help.

We do need your ongoing financial support as well, to keep ‘spreading the word’. Please consider a donation to Prevent Vitamin D Deficiency for our future health.

Onwards!

Carole Baggerly

Director, GrassrootsHealth
carole@grassrootshealth.org

4 causes of aging

In his book, “The Most Effective Ways to Live Longer”, Johnny Bowden identifies what he calls “the four horsemen of aging,” which are thought to be dangerous processes that age our bodies and are triggered by the foods we eat and the lifestyles we lead. Conquer these four horsemen, Bowden contends, and you can slow down the aging process.

1. Free radicals: Free radicals are chemically unstable molecules that attack your cells and damage your DNA. You can limit your exposure to them by avoiding cigarettes, trans fats, charred meats, and other sources.

Organic fruits and vegetables will also limit your exposure to pesticides and herbicides, which contain the harmful molecules.

2. Inflammation: Inflammation is a major player in many diseases of aging, including cancer, diabetes, heart disease, and Alzheimer’s. One way to avoid it is to follow a Mediterranean-style diet.

Other great anti-inflammatory foods include turmeric, dark chocolate, and the anti-aging chemical resveratrol. Exercise is another great way to lower inflammation.

3. Glycation: Glycation is what happens when sugar mixes with proteins and fats to form molecules that promote aging. Advanced glycation end products, or AGEs (Isn’t that an appropriate acronym?), are thought to accelerate your aging process by churning out free radicals and promoting inflammation. One way to avoid ingesting AGEs is to turn down the heat when you cook. The browning effect of high-heat cooking causes these molecules to form. Limiting your intake of sugar-filled foods in general will also help.

4. Stress: Stress initiates the release of a variety of hormones that make your pulse race and cause your blood pressure to rise. The hormone cortisol, released to lessen these effects, also creates problems when it remains chronically elevated. Try practicing relaxation techniques to help manage stress, and get enough sleep every night.

U.S. News & World Report July 29, 2010

Benefits of Green Tea

Tea is the second most widely consumed beverage in the world. Although water is the most widely consumed beverage, still, hundreds of millions of people drink tea every day based on health benefits and taste. Tea comes in three main varieties, black, green, and oolong. Green tea (Camellia sinesis), is believed to have the most health benefits thanks to the way it’s processed. Green tea is made from unfermented leaves, which contain the highest concentration of powerful antioxidants. Antioxidants such as polyphenols in green tea neutralize free radicals and reduce or help prevent some of the damage they cause.

Free radicals are damaging compounds in the body that alter cells, tamper with DNA (genetic material), and cause cell death. According to the University of Maryland Medical Center free radicals occur naturally in the body, but environmental toxins (including ultraviolet rays from the sun, radiation, cigarette smoke, and air pollution) also give rise to these damaging particles. Many scientists believe that free radicals contribute to the aging process as well as the development of a number of health problems including cancer and heart disease. Based on studies using human subjects, animals, and in laboratory experiments, green tea is useful for:

-Arthritis
-Atherosclerosis
-Cancer
-Colds
-Diabetes
-High Cholesterol
-Inflammatory Bowel Disease (IBD)
-Influenza
-Liver Disease
-Obesity
-Tooth Decay
-Weight Loss

Green tea has been used as a stimulant, diuretic, astringent, and to improve heart health throughout the ages in China, India, Japan, and Thailand. Other traditional include improving mental processes, promoting digestion, regulating body temperature and blood sugar, and treating flatulence (gas).

In addition to tea leaves, green tea is available in capsule form and liquid form made from leaves and leaf buds. A cup of green tea contains 50-150 mg of antioxidant (polyphenols). Decaffeinated green tea also contains polyphenols, but they are concentrated. If you are sensitive to caffeine, caffeine-free supplements are available.

U.S. News and World Report; Best hospitals of 2010-2011

US News and World Report ranks America’s hospitals? They also rank colleges, law schools and medical schools. I’ve read that these institutions go through great lengths to improve their standings because these reports have so much influence. This year, only 152 of the 4,852 hospitals evaluated performed well enough to rank in any specialty. And of the 152, just 14 qualified for a spot in the Honor Roll by ranking at or near the top in six or more specialties. Below are the top 3 in three major categories.

Cancer:
#1 University of Texas M.D. Anderson Cancer Center
Houston, TX
#2 Memorial Sloan-Kettering Cancer Center
New York, NY
#3 Mayo Clinic
Rochester, MN
#9 Cleveland Clinic
Cleveland, Ohio

Heart and Heart Surgery:
#1 Cleveland Clinic
Cleveland, OH (Hometown pride)
#2 Mayo Clinic
Rochester, MN
#3 Johns Hopkins Hospital
Baltimore, MD

Neurology and Neurosurgery:
#1 Johns Hopkins Hospital
Baltimore, MD
#2 Mayo Clinic
Rochester, MN
#3 Massachusetts General Hospital
Boston, MA
#6 Cleveland Clinic
Cleveland, Ohio

Go to USNews see all the rankings of the best hospitals including the top children’s hospitals

New research: cut back on carbs, live longer

According to the 2002 United States Life Tables, In 2002 the average person in the US could expect to live a little over 19 years longer than in 1920. But does longevity come with a healthy life? Not for most. Arthritis, Alzheimer’s, cardiovascular disease, deteriorating senses, and other diseases and conditions all come with age. However, new research may have uncovered a true fountain of youth, and it may be as simple as cutting down on consuming carbs.

Professor Cynthia Kenyon, a US genetisist, has discovered that the carbohydrates we eat like bananas, potatoes, bread, pasta, and cakes directly affect two key genes that govern youthfulness and longevity.

But what Professor Kenyon found out was why ­drastically reducing calories has such a remarkable effect.

She discovered that it changed the way two crucial genes behaved. It turned down the gene that controls insulin, which in turn switched on another gene, which acted like an elixir of life.

‘We jokingly called the first gene the Grim Reaper because when it’s switched on, the lifespan is fairly short,’ she explains.

The ­second ‘elixir’ gene seems to bring all the anti-aging benefits.

Professor Kenyon has changed her diet as a result of her research.

‘Carbo­hydrates, and especially refined ones like sugar, make you produce lots of extra insulin. I’ve been keeping my intake really low ever since I discovered this.

‘I’ve cut out all starch such as potatoes, noodles, rice, bread and pasta. Instead I have salads, but no sweet dressing, lots of olive oil and nuts, tons of green vegetables along with cheese, chicken and eggs.

‘I’ll have a hamburger without a bun and fish without batter or chips. I eat some fruit every day, but not too much and almost no processed food. I stay away from sweets, except 80 per cent chocolate.’

She is adamant it will be well worthwhile. ‘You could have two completely different careers if you could stay healthy to 90,’ she says. ‘How fascinating that would be.’

READ MORE

The dark side of soy

The vast majority of soy at your local market is not a health food. 91% of soy grown in the US is genetically modified (GM) soy that is contaminated with large pesticide residues. The genetic modification is done to impart resistance to the toxic herbicide Roundup, so they can spray it over the soy plants to improve crop production by killing the weeds. This is solely meant to increase farming efficiency and provide you with less expensive soy. In other words, cheap as opposed to healthy.

For centuries, contrary of what Americans have been told, Asian people have been consuming non-GM fermented soy products such as natto, tempeh, and soy sauce in SMALL amounts. Western food processors separate the soybean into two commodities?protein and oil. And there is nothing natural or safe about these products that many Americans consume.

Dr. Kaayla Daniel, author of The Whole Soy Story, points out thousands of studies linking soy to malnutrition, digestive distress, immune-system breakdown, thyroid dysfunction, cognitive decline, reproductive disorders and infertility?even cancer and heart disease.

Here is just a sampling of the health effects that have been linked to soy consumption:

* Breast cancer
* Brain damage
* Infant abnormalities
* Thyroid disorders
* Kidney stones
* Immune system impairment
* Severe, potentially fatal food allergies
* Impaired fertility
* Danger during pregnancy and nursing

Soy proponents will argue that soy-based foods (they lump the fermented ones with the unfermented) will protect you from everything from colon, prostate and breast cancer to strokes, osteoporosis, and asthma. However, proponents never mention the studies that illuminate soy?s downside and all of the dangers posed to your health, which are based on sound research.

Another unfortunate fact is that 80 percent of the world?s soy is used in farm animal feed, which is why soy production is contributing to deforestation. Some soy propagandists have suggested that the solution to this is for all of us to become vegetarians?a reckless recommendation rooted in total ignorance about nutrition?whereas a far better solution is a major overhaul in how farm animals are fed and raised.

Thumbs up review of Nutrition and Physical Degeneration by Weston A Price, DDS

Nutritional and Physical Degeneration is one of the most ground-breaking books ever written on the link between nutrition and health. Dr. Weston A. Price, a dentist from Cleveland, became very disturbed by what he saw in his patients. He started to see a link between the decay he found in the mouths of his patients and pathologies found elsewhere in the body like diabetes, arthritis, osteoporosis, gastrointestinal complaints, and more. Dr. Price also found that crowded, crooked teeth were becoming more and more common, along with facial deformities like overbites, narrow faces, lack of well defined cheek bones, and underdevelopment of the nose. Dr. Price did not believe these problems to be in any way normal; He believed they were the result of poor nutrition. The worse a person?s diet was the more decay he found in their mouth. The more decay a person had in their mouth, the higher the rate of pathologies in other areas of the body.

More than 70 years ago Dr. Price decided to search the world for primitive people who lived entirely on indigenous foods. His travels took him from islands in the South Seas to Alaska to Africa and many places in between. He visited Australian Aborigines, Swiss villages, Eskimos, traditional American Indians, Amoazonian Indians, African tribes, and more. Dr. Price and his wife Florence traveled for ten years during the 1920′s and 30′s when groups of people completely isolated from civilization could be found.

Throughout his travels, Dr. Price kept a record of his findings with pictures and detailed assessments. What he found, to be called astounding, is an understatement. Dr, Price discovered that primitive people untouched by civilization, who subsided on a diet of indigenous food, had outstanding physical development with little to no dental problems, heart disease, diabetes, or any other diseases we know believe to be a normal consequence of life.

Dr. Price?s findings were not surprising to other investigators and explorers. However, the excepted explanation at the time was that primitive people were ?racially pure? and that the maladies we see in civilization were due to ?race mixing?. This theory was untenable to Dr. Price who found that the individuals in groups he studied who abandoned their traditional diets for foods provided by traders or missionaries, or who moved to a more civilized area were found to develop tooth decay and degenerative conditions.

The diets of these primitive groups of people were vastly different. Some were mostly cooked food while in others most of the food was consumed raw including animal sources. Some diets were based on sea food, others on domestic animals and others on wild game. Some diets were based on dairy while others consumed a variety of fruits and vegetables and grains.

The common thread between all the groups Dr. Price investigated was none of them contained any refined devitalized foods like white sugar, flour, pasteurized or skim milk, and refined or hydrogenated vegetable oils. All the diets contained animal foods of some type and some salt. Dr. Price analyzed the primitive diets and found they all contained four times the amount of water soluble vitamins and minerals, and ten times the amount of fat soluble vitamins compared to the modern American diet.

Unfortunately, Nutrition and Physical Degeneration, the permanent record of his travels, is nonexistent to today?s modern medical community. This book is more important to our health and welfare today than it was 60 years ago. Our food supply, if it could be classified as food, is devoid of almost all nutritive value. We need to incorporate the fundamentals of primitive nutrition and return to nutrient dense whole food. We need to get back to local farming and turn away from manmade supermarket garbage that is destroying our health.

Anyone interested in becoming truly healthy needs to read Nutrition and physical degeneration

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